Botanical Overview
Vitis vinifera (semen), commonly known as grape seed, belongs to the Vitaceae family. The seed of the grape fruit is the primary part used medicinally, valued chiefly for its potent antioxidant properties.
Energetics
The seeds are considered to have a neutral temperature and drying moisture quality, with astringent and bitter tastes. They are tonifying in nature, primarily influencing the blood system.
Primary Actions
- Antioxidant
- Anti-inflammatory
- Venotonic
- Cardioprotective
Indications
Western
- Chronic venous insufficiency
- Varicose veins
- Edema
- Hypertension
- Oxidative stress
Syndromes
- Poor circulation
- Vascular fragility
- Hyperlipidemia
TCM
No well-documented traditional uses.
Ayurveda
No well-documented traditional uses.
Unani
No well-documented traditional uses.
Constituents & Mechanisms
The seed is rich in oligomeric proanthocyanidins, flavonoids, polyphenols including resveratrol, which contribute to its antioxidant and vascular protective effects.
Dosage & Preparations
- Extract standardized to 95% proanthocyanidins, 100–300 mg daily
- Available as capsules, tablets, or powder
Safety & Contraindications
Grape seed extracts are generally well tolerated. Caution is advised in individuals with bleeding disorders or those using anticoagulant/antiplatelet medications due to increased bleeding risk. Data on safety during pregnancy and lactation is insufficient; use is not recommended. Allergic reactions are rare but possible.
Astrological Correspondences
No reliable sources found for planetary or elemental rulers for grape seed.
Selected References
- European Medicines Agency (EMA) Herbal Monograph: Vitis vinifera L., semen (Grape Seeds), 2019
- Bagchi D et al. Therapeutic potential of grape seed proanthocyanidin extract in cardiovascular disease: A review, PubMed, 2004
- Natural Medicines Database: Grape Seed Extract, 2023