Botanical Overview
Huperzia serrata, commonly known as Chinese club moss or toadstool clubmoss, is a member of the Lycopodiaceae family. This plant is native to China and parts of Southeast Asia. The aerial parts and leaves of the plant are traditionally used for medicinal purposes.
Energetics
The energetics of Huperzia serrata are generally considered neutral in temperature and moisture, with a bitter taste. It has a tonifying effect, primarily supporting the nervous system.
Primary Actions
- Cognitive enhancer
- Neuroprotective
- Acetylcholinesterase inhibitor
Indications
Western
- Cognitive decline
- Memory impairment
- Mild to moderate Alzheimer’s disease symptoms
- Myasthenia gravis
Syndromes
- Alzheimer’s disease
- Dementia
- Neuromuscular disorders
TCM
- Forgetfulness
- Dizziness
- Weakness
- Muscle fatigue
Syndromes
- Kidney essence deficiency
- Liver Yang rising
- Qi and blood deficiency
Ayurveda
No well-documented traditional indications available.
Unani
No well-documented traditional indications available.
Constituents & Mechanisms
Huperzia serrata contains bioactive alkaloids such as huperzine A and other lycopodium alkaloids, which have acetylcholinesterase inhibitory activity contributing to its neuroprotective and cognitive-enhancing effects.
Dosage & Preparations
- Standardized extract containing 0.1-0.5% huperzine A: 50-200 mcg daily
- Tincture (1:5 in ethanol 40%): 2-5 mL daily
- Powdered herb infusions: traditional dosages vary
Safety & Contraindications
Generally well-tolerated when used at recommended doses. Possible side effects include nausea, vomiting, diarrhea, blurred vision, and muscle cramps. Use caution with cardiovascular disease or asthma. Avoid use during pregnancy and lactation due to insufficient safety data.
Astrological Correspondences
No credible astrological or elemental correspondences established.
Selected References
- Huperzine A from Huperzia serrata: a potential therapeutic agent for Alzheimer’s disease
- WHO Monographs on Selected Medicinal Plants: Huperzia serrata
- Chinese Pharmacopoeia: Huperzia serrata – Chinese club moss
- NIH MedlinePlus: Huperzine A