Botanical Overview
Harpagophytum procumbens, commonly known as Devil’s Claw or Grapple Plant, belongs to the family Pedaliaceae and is native to Southern Africa including regions such as Namibia, Botswana, and South Africa. The medicinally used part is the root, especially the secondary tuberous roots.
Energetics
The root is considered cooling and drying in nature, with a distinctly bitter taste. Its tonic effect is primarily relaxing, acting on musculoskeletal and digestive systems.
Primary Actions
- Anti-inflammatory
- Analgesic
- Digestive tonic
- Cholagogue
- Antirheumatic
Indications
Western
- Joint pain
- Inflammation
- Digestive complaints
- Lower back pain
- Arthritis
- Muscle pain
Syndromes
- Osteoarthritis
- Rheumatoid arthritis
- Dyspepsia
- Inflammatory conditions
TCM
Not traditionally used or documented.
Ayurveda
Not traditionally used or documented.
Unani
Not traditionally used or documented.
Constituents & Mechanisms
The primary bioactive constituents include the iridoid glycosides harpagoside and related phenolic compounds, which contribute to anti-inflammatory and analgesic effects primarily by modulating prostaglandin synthesis and inflammatory pathways.
Dosage & Preparations
- Tincture 1:5 (40% ethanol), 2-5 mL, 1-3 times daily
- Decoction using 2-4 g dried root, 1-2 times daily
- Powdered root, 1-3 g daily
Safety & Contraindications
Harpagophytum procumbens is generally safe when used within recommended doses. Some individuals may experience gastrointestinal discomfort. It is contraindicated in pregnancy, particularly due to potential uterine stimulation, and in people with peptic ulcers or gallstones. Use with caution in patients on anticoagulants or antidiabetic medication because of possible interactions.
Astrological Correspondences
No confidently sourced planetary or elemental rulers available.
Selected References
- Assessment report on Harpagophytum procumbens DC., radix – European Medicines Agency, 2016
- Devil’s Claw – NCCIH
- WHO Monographs on Selected Medicinal Plants – Volume 2: Harpagophytum procumbens DC. (devil’s claw) – WHO, 2002