Coptis; Berberis spp.

Botanical Overview

Latin name: Coptis; Berberis spp.

Family: Berberidaceae

Parts used: Root, Rhizome, Bark, Stem

Common names: Barberry, Goldthread, Oregon grape

Energetics

Temperature: Cooling

Moisture: Drying

Tastes: Bitter, Astringent

Directionality: Not well characterized

Tonicity: Tonifying

Qi/Blood/Fluid: Qi tonic

Primary Actions

  • Antimicrobial
  • Bitter
  • Choleretic
  • Hepatoprotective
  • Anti-inflammatory

Indications

Western

  • Indigestion
  • Diarrhea
  • Jaundice
  • Infections
  • Liver dysfunction
  • Skin infections

Syndromes

  • Dyspepsia
  • Hepatic congestion
  • Bacterial infections

TCM

  • Damp-heat
  • Diarrhea
  • Jaundice
  • Dysentery

Syndromes

  • Damp-heat in liver and gallbladder
  • Toxin accumulation

Ayurveda

No well-documented traditional uses found.

Unani

No well-documented traditional uses found.

Constituents & Mechanisms

Contains isoquinoline alkaloids such as berberine, berberastine, coptisine, columbamine, and palmatine, responsible for antimicrobial, bitter, and choleretic activities.

Dosage & Preparations

  • Decoction: 1-3 g dried root 2-3 times daily
  • Tincture: 1:5 in 40% ethanol, 2-5 mL 1-3 times daily

Safety & Contraindications

Generally well tolerated when used appropriately. Avoid during pregnancy due to potential uterine stimulant effects; caution in lactation. Possible interactions with medications metabolized by cytochrome P450 enzymes and additive effects with antihypertensives.

Astrological Correspondences

No reliable data found.

Selected References

  • Berberis vulgaris L., cortex – European Medicines Agency (2011)
  • Berberis and Coptis Species Phytochemistry and Pharmacology – Wagner & Bladt (1996)
  • Berberis vulgaris – PFAF database
  • Coptis chinensis – Chinese Herbal Medicine Materia Medica (Bensky, 2004)