Botanical Overview
Coleus forskohlii (syn. Plectranthus barbatus) belongs to the Lamiaceae family. Common names include Coleus, Indian coleus, and Makandi. The medicinally used part is primarily the root. Native to India and Southeast Asia, this plant has a long history of use in traditional Ayurvedic medicine.
Energetics
The root of Coleus forskohlii is considered neutral in temperature and moisture with bitter and pungent tastes. It is classified as tonifying in its effects.
Primary Actions
- Cardiotonic
- Vasodilator
- Bronchodilator
- Hypotensive
- Lipolytic
Indications
Western
- Hypertension
- Asthma
- Glaucoma
- Heart failure
- Obesity
- Celiac disease
Syndromes
- Cardiovascular insufficiency
- Bronchospasm
- Metabolic dysfunction
TCM
No widely established indications documented.
Ayurveda
- Cough
- Bronchitis
- Congestive heart failure
- Obesity
Syndromes
- Rakta (blood) disorders
- Kapha and Vata imbalance
Unani
- Weak heart
- Respiratory difficulties
Constituents & Mechanisms
The principal bioactive constituent is forskolin, a labdane diterpene known for activating adenylate cyclase resulting in increased cyclic AMP levels. The root also contains volatile oils, flavonoids, and other phenolic compounds.
Dosage & Preparations
- Root extract standardized to 10% forskolin, 250–500 mg daily
- Tincture 1:5 40% ethanol, 2–5 mL one to three times daily
- Powdered root 1–3 g daily
Safety & Contraindications
Coleus forskohlii is generally safe when used at recommended doses. Use with caution during pregnancy and lactation due to limited safety data. It may potentiate hypotensive drugs and increase bleeding risk when combined with anticoagulants; avoid in hypotension or bleeding disorders.
Astrological Correspondences
No reliably sourced planetary or elemental rulers identified for Coleus forskohlii.
Selected References
- Herbal Medicine: Biomolecular and Clinical Aspects, Benzie & Wachtel-Galor, 2011
- Forskolin: A labdane diterpene activating adenylate cyclase, Seamon et al., 1981
- Indian Pharmacopoeia, 2018
- Therapeutic Potential of Coleus forskohlii Briq., Gawali & Ghante, 2017