Botanical Overview
Coptis; Berberis; Mahonia spp. are members of the Berberidaceae family, commonly known as goldthread, barberry, Oregon grape, and mahonia. These plants are native to regions including North America, East Asia, and Europe. The medicinal parts primarily used are the roots and root bark.
Energetics
The energetics of these species are characterized by a cooling temperature and drying moisture quality. Their taste profile is predominantly bitter. Other energetic attributes such as directionality or tonicity are not well defined.
Primary Actions
- Antimicrobial
- Bitter
- Cholagogue
- Hepatoprotective
- Anti-inflammatory
Indications
Western
- Dyspepsia
- Infections (bacterial, fungal)
- Hepatic congestion
- Skin conditions (psoriasis, eczema)
Syndromes
- Liver and gallbladder dysfunction
- Chronic inflammatory conditions
- Bacterial infections
TCM
- Digestive disturbances
- Damp-heat conditions
Syndromes
- Liver Qi stagnation
- Damp-heat in Liver and Gallbladder
Ayurveda
No well-supported traditional Ayurvedic uses were identified for these species.
Unani
No well-supported traditional Unani uses were identified for these species.
Constituents & Mechanisms
The key phytochemicals include isoquinoline alkaloids such as berberine, coptisine, and palmatine. These constituents contribute to antimicrobial, anti-inflammatory, and hepatoprotective activities.
Dosage & Preparations
- Tincture 1:5 in 45% ethanol, 2-4 mL taken 2-3 times daily
- Decoction of root bark, 2-5 grams 1-3 times daily
Safety & Contraindications
These plants are generally safe within traditional dosing parameters. Use during pregnancy and lactation is contraindicated due to uterotonic potential and insufficient safety data. Gastrointestinal upset may occur. Potential interactions exist with drugs metabolized by cytochrome P450 enzymes; caution advised.
Astrological Correspondences
No confidently sourced planetary or elemental rulers could be identified.
Selected References
- Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.
- Plants For A Future (PFAF) database – Coptis chinensis
- World Health Organization Monographs on Selected Medicinal Plants, Volume 1
- European Medicines Agency Herbal Monograph on Berberis vulgaris L., Cortex