Hedyotis diffusa

Botanical Overview

Hedyotis diffusa, commonly known as Oldenlandia diffusa or Bai Hua She She Cao, is a herbaceous plant in the Rubiaceae family. It is native to East and Southeast Asia, particularly valued in Traditional Chinese Medicine (TCM). The whole plant is used medicinally, especially for its anti-inflammatory and detoxifying properties.

Energetics

This herb is characterized as cooling and moistening in temperature and moisture, with a bitter and slightly sweet taste. Its energetic actions are descending, helping to clear heat and toxins. It is generally relaxing on the body’s qi.

Primary Actions

  • Anti-inflammatory
  • Anticancer
  • Detoxifying
  • Antibacterial
  • Diuretic

Indications

Western

  • Inflammation
  • Infection
  • Cancer-related symptoms
  • Detoxification

Syndromes

  • Chronic inflammation
  • Urinary tract infections
  • Cancer adjunct therapy

TCM

  • Skin ulcers
  • Damp-heat conditions
  • Toxic swellings
  • Fever

Syndromes

  • Heat toxin
  • Damp-heat
  • Blood stasis

Ayurveda

No well-supported traditional uses identified.

Unani

No well-supported traditional uses identified.

Constituents & Mechanisms

Hedyotis diffusa contains iridoids, flavonoids, anthraquinones, polyphenols, and alkaloids that support its anti-inflammatory and anticancer activities.

Dosage & Preparations

  • Decoction: 10-30 grams daily
  • Ethanol extract standardized for iridoids
  • Powdered herb: 5-15 grams daily

Safety & Contraindications

This herb is generally well tolerated but should be avoided during pregnancy and lactation due to insufficient safety data. Caution is advised in individuals with cold-damp body constitutions. Monitor patients using concurrent immunosuppressive or chemotherapeutic drugs.

Astrological Correspondences

No reliably sourced planetary or elemental rulers are established for Hedyotis diffusa.

Selected References

  • Phytochemistry and Pharmacology of Hedyotis diffusa, Liu et al., Journal of Ethnopharmacology, 2010
  • Chinese Herbal Medicine: Materia Medica, Bensky, Clavey & Stöger, 2004
  • Anti-inflammatory and Anticancer Effects of Hedyotis diffusa, Wang et al., Phytotherapy Research, 2015